The decrease in expense for 2009 is due to the substantial primarily completion of two significant medical studies by the third quarter of 2009 related to the company’s budiodarone and tecarfarin product candidates. General and administrative expenses through the fourth quarter and full year 2009 were $2.3 million and $10.2 million respectively. For the same periods of 2008, G&A expenses totaled approximately $1.9 million and $10.1 million, respectively. The upsurge in expenses during the fourth quarter of 2009 in comparison with the same period in 2008 was primarily because of costs linked to our restructuring of procedures announced in October 2009 totaling approximately $375,000. G&A expenses for the full-year 2009 when compared with 2008 had been the same approximately year over year..A few patients might not improve and will need to explore further treatment options. In some cases, a palliative strategy is used to stop the spread of seizures, when the actual seizure focus cannot accurately be determined. One particular approach involves reducing the nerve fibers linking both sides of the brain through a corpus callosotomy. The corpus callosum can be a band of nerve fibers located deep in the brain that connects both sides of the brain. The hemispheres are helped by it share information, but it also plays a part in the spread of seizure impulses from one side of the mind to the various other. A functional hemispherectomy is a medical procedure performed in these cases, where the epileptic, nonfunctioning hemisphere is usually disconnected from the rest of the, normal hemisphere to be able to stop the seizures.