Results Study Sets A total of 468 individuals with HIV-1 infection were included in the two partially overlapping study sets . Most of the individuals were European American guys . Approximately 80 percent of the individuals reported symptoms in keeping with an severe retroviral syndrome11 around the time of their estimated day of infection. Participants entered the study at a median of 10 weeks following the estimated day of infection . The proportion of individuals presenting within each one of the laboratory-defined levels of primary HIV-1 contamination10,12 varied .For analysis of the principal efficacy end point, just events that didn’t include a pump interaction, which were not preceded by a nonphysiologic sensor glucose rate of switch , and that lasted for a lot more than 20 minutes following the 1st sensor glucose worth was 65 mg per deciliter or much less were analyzed. Events separated by significantly less than 30 minutes had been counted as an individual event. The magnitude and duration of each qualified hypoglycemic event were used to calculate the AUC for sensor glucose values of 65 mg per deciliter or less. Event AUC data had been analyzed with the use of both primary and log-transformed scales. Mean log-transformed event AUCs were estimated and compared through a superiority test with a one-sided significance level of 0.025.