Activation of MMP-9 enzyme leads to behavioral problems connected to chronic stress A group from the EPFL Mind Mind Institute has discovered an important synaptic system: the activation of a cleaving enzyme, leading to behavioral problems linked to chronic stress. Exactly why is it that when people are too stressed they are generally grouchy, grumpy, nasty, distracted or forgetful? Researchers from the mind Mind Institute at EPFL possess simply highlighted a fundamental synaptic mechanism that explains the partnership between chronic stress and the loss of social skills and cognitive impairment. When triggered by tension, an enzyme attacks a synaptic regulatory molecule in the brain stendra .
With further study, this could lead to a far more effective and safer drug strategy for glucose regulation and excess weight loss. Obici is currently conducting further studies to look for the specific location of the CB1 receptor in the sympathetic nervous program that activates the calorie-burning, glucose-eating properties of brown adipose tissue. Our results suggest that the capability of brown adipose tissue to burn calorie consumption and consume glucose is normally impaired in weight problems and type 2 diabetes. If we could find a highly effective and safe way to reactivate the brownish adipose tissue’s calorie-burning up properties, this may represent a breakthrough in the search of more effective drugs against weight problems and diabetes,, Obici adds..