And above all, massive intrusions on our individual relationships. These complaints could be dismissed as growing pains, born of resistance to change. But transitional chaos should be distinguished from enduring damage. Even so, the researchers found amazing EHR-induced distress. It is eminently quantifiable and yet stubbornly not. The purpose of widespread EHR adoption, as envisioned by the National government in 2008, was allowing a changeover from volume-centered to value-based payments: a digital infrastructure was needed for measuring quality.The primary reasons for switching regimens consist of virologic, immunologic, or scientific drug and failure toxicity or intolerance. Switching regimens in suppressed patients to reduce toxicity virologically, improve adherence and tolerability, and avoid medication interactions can be done by switching 1 or more agents in the regimen. Confirmed treatment failure should be addressed promptly and multiple elements considered, the researchers write. Though it is essential to intensify efforts to locate a cure for persons who already are infected and a highly effective vaccine for individuals who are not, most of the tools needed to control the HIV/AIDS pandemic are already at hand.