Further, more than half of those surveyed who have the condition think that over-the-counter medicines will treat the symptoms adequately, even though no over – the-counter treatment has been proven to effectively treat the infection, and no OTC treatment is usually approved for this use. The survey, conducted in May 2004, which included more than 900 adults, also uncovered that nearly nine in 10 consumers age 35 and old who have symptoms of fungal nail an infection recognize that changes in their toenails suggest a health problem, but nearly one-fourth have waited a calendar year or more before carrying out anything about it and nearly one-third say they possess not sought treatment however. The condition also has a psychological and emotional impact: nearly two-thirds of these with onychomycosis would experience better about themselves if indeed they had healthful looking nails.Lists the main top features of the five sufferers we studied. Sufferers 1 and 2, who had been siblings born to consanguineous parents of Aramean descent, presented with neonatal sepsis. Their prolonged pedigree is denoted SCN-I . Their workup in the first year of existence found severe neutropenia with a paucity of mature neutrophils in the peripheral bloodstream and bone marrow. Bone marrow smears contained few granulocytes beyond the stage of promyelocytes or myelocytes . Erythrocyte counts were normal. Platelet counts in Individual 1 ranged from 73,000 to 425,000 per cubic millimeter, whereas Individual 2 had regular platelet counts. Both patients got prominent subcutaneous veins unusually, venous angiectasia, or both ; Individual 1 had a sort 2 atrial septal defect , and Patient 2 acquired cor triatriatum and hepatosplenomegaly.