All individuals gave written educated consent. Study Treatment and Design The study was a randomized, double-blind, placebo-controlled, phase 3 trial conducted at 77 centers in France, Belgium, and Switzerland. From July 2006 through August 2008 Patients were recruited. After undergoing transplantation, sufferers were randomly assigned in a 1:1 ratio to receive either consolidation treatment with lenalidomide , accompanied by maintenance therapy with lenalidomide , or the same consolidation treatment with lenalidomide, accompanied by maintenance therapy with placebo. Before September 2006 , individuals were randomly designated to the maintenance routine just . Treatment was continued before patient withdrew consent, the disease progressed, or unacceptable toxic results happened.Professor Debbie Sharp said: Few interventions have already been proved to considerably help patients with persistent back discomfort in the long run. Lessons in the Alexander technique present an individualised approach to develop skills that help people recognise, understand, and avoid poor habits affecting postural tone and neuromuscular coordination. The practice and theory of the technique support the hypothesis that it might potentially reduce back pain by limiting muscles spasm, strengthening postural muscle tissue, improving coordination and flexibility, and decompressing the backbone. The trial was funded by the Medical Research Council and the NHS Development and Research fund.