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Lastly, a prostatectomy is the removal of the prostate gland itself. Radiotherapy entails the usage of radiation to take care of the cancer, which always bears the risk of contracting radiation poison or even another form of cancer. Androgen deprivation, whether by castration or estrogen replacement therapy, will certainly reduce the mail sex drive and cause impotency regarding castration. A prostatectomy, among other side effects, has been shown to cause impotence in 60 percent of patients, and incontinence in 39 percent of patients.